Invitro+Jobs

The U.S. Food and Drug Administration (FDA) is currently evaluating whether an in vitro test method—known as the pH cycle test model—can be included in OTC Monograph M021 as an alternative test method to demonstrate the efficacy of fluoride toothpaste. Data submissions are being requested for this purpose. The monograph regulates the conditions under which over-the-counter caries prevention products are considered safe and effective.

Clinical trials of two new Alzheimer's drugs—which target the tau protein instead of beta-amyloid proteins—have yielded initial results suggesting that the progression of Alzheimer's is apparently even more complex than previously thought.

As part of the “Faces Behind Science” series, the European Commission’s Joint Research Center has recently featured Dr. Maurice Whelan, Director of the European Validation Authority (EURL ECVAM), in a short film. He talks about his work and new animal-free approaches (NAMs).